ISSN 1301 - 0883 | E-ISSN: 1309-3886
Eastern Journal of Medicine
Multiple Sclerosis: Does the Apparent Diffusion Coefficient Have a Diagnostic Efficiency ın Active - Inactive Demyelinating Plaques? [Eastern J Med]
Eastern J Med. 2023; 28(3): 495-498 | DOI: 10.5505/ejm.2023.69260

Multiple Sclerosis: Does the Apparent Diffusion Coefficient Have a Diagnostic Efficiency ın Active - Inactive Demyelinating Plaques?

Harun Arslan1, Muhammed Bilal Akıncı2
1Van Yuzuncu Yil University Faculty of Medicine, Department of Radiology, Van, Turkey.
2Gumushane State Hospital

INTRODUCTION: In multiple sclerosis (MS) patients, in the evaluation of active and inactive plaques, the contribution of Apparent Diffusion Coefficient (ADC) measurements to the diagnosis was investigated.
METHODS: A total of 88 patients, 66 women and 22 men, were examined in this study. The patients’ ages ranged from 19 to 53; the median age was 30.5 ±8.1. ADC measurements were taken of every plaque from active and inactive plaques using contrast enhancement (CE) Magnetic Resonance İmaging MRI. ADC measurements were considered active (92) or inactive (230) in accordance to their contrast enhancement, and specificity and sensitivity values were checked.
RESULTS: We examined and comparison the descriptive statistics results of MS plaques in relation to the active and inactive groups in terms of ADC measurement values. Accordingly, the averages for the active and inactive groups, respectively, were found to be 1.011 and 1.245, and the difference was statistically significant between these two averages (p<0.01). Accordingly, our study shows that ADC measurements are higher in the inactive group.
DISCUSSION AND CONCLUSION: ADC measurements can be a useful imaging modality in the differentiation of MS plaques in diffusion-weighted imaging.

Keywords: Apparent coefficient diffussion, active-inactive plaque, Magnetic resonance imaging

Corresponding Author: Harun Arslan, Türkiye
Manuscript Language: English
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