Severe acute necrotizing pancreatitis after endoscopic biopsy of the minor duodenal papilla

Endoscopic biopsies are occasionally taken from the minor duodenal papilla when abnormal appearance of the minor duodenal papilla is encountered during esophagogastroduodenoscopy. Minor complications such as bleeding could occur after biopsy, however acute pancreatitis is a very rare complication after biopsy of the minor duodenal papilla. We report a case of severe acute necrotizing pancreatitis following biopsy of the minor duodenal papilla.