Eastern J Med. 2017; 22(2): 53-56 | DOI: 10.5505/ejm.2017.63825

Does HRT Change Ýntraocular Pressure in Postmenopausal Women ?

Coþkun Sait Özcan¹, Egemen Harun Tolunay², Deniz Özarslan Özcan³, Fatih Mehmet Adýbelii⁴, Neþe Gül Hilali⁵, Korhan Kahraman^6
1Metrolife Private Hospital,Þanlýurfa
²Van Yuzuncu Yýl University, Obstetrics And Gynecology,van
³Akçakale State Hospital, Þanlýurfa, Turkey
⁴Harran University,Ophtalmology Department,Þanlýurfa
⁵Harran University School of Medicine, Department of Obstetrics and Gynaecology, Þanlýurfa, Turkey
⁶Koru International Hospital,Ankara

INTRODUCTION: We aimed to investigate the changes of intraocular pressure in menopause patients with the use of hormone replacement therapy (HRT).
METHODS: Totally 137 postmenopausal women were evaluated in the study. 61 of them were under the treatment of HRT due to the menopausal symptoms. 76 women did not receive treatment. IOP ( intraocular pressure ) was measured with Goldmann tonometer (Optilasa,S.L., Madrid, Spain) in both groups.
RESULTS: In the HRT treatment group ( study group), mean values of IOP for 2 eyes in the first visits was 15.4 ± 1.7 mmHg and 13.9 ± 1.4 mmHg after 6 months use of HRT, respectively (p<0.05). In the non-HRT group (control group) mean values of IOP for 2 eyes in the first visits was 14.4 ± 1.4 mmHg and 14.3 ± 1.4 mmHg after six months, respectively( p˃0.05).
DISCUSSION AND CONCLUSION: HRT use and regular measurement of IOP seems to prevents to reduce risk the of glaucoma in these patients unless there are strong evidence that glaucoma does not occur in women on HRT.

Keywords: intraocular pressure, menopause, hormone replacement therapy, HRT, glaucoma, estrogen and progesterone.

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