Comparative Evaluation of MDA Levels During Aerobic Exercise in Young Trained and Sedentary Male Subjects

INTRODUCTION: The impacts of acute aerobic exercise on oxidative stress as determined altered MDA levels have been examined in young trained and sedentary male subjects.
METHODS: Total of 20 (10 trained and 10 sedentary) male subjects performed an aerobic cycling exercise at the anaerobic threshold for about 30 min. Pre and post exercise venous blood samples were taken and analysed for MDA using HPLC methods. Wilcoxon and Mann Whitney U test were used to analyse the significance of the data.
RESULTS: Acute exercise caused a systematic increases in MDA levels in trained (36.2%) and sedentary (55.4%) subjects during exercise (p<0.001). The increase in MDA levels were higher in sedentary subjects (0.79±0.08 µmol/L vs. 1.02±0.5 µmol/L) compared to trained subjects (0.73±0.05 µmol/L vs. 0.97±0.07 µmol/L) (p<0.001).
DISCUSSION AND CONCLUSION: Acute exercise may cause higher levels of increase in oxidative stress as determined MDA levels in sedentary subjects. Thus the sedentary subjects should pay more attention to the performed physical activities.