Pre-operative mean corpuscular volume, red cell distribution width and neutrophil-to-lymphocyte ratio in patients with enchondroma

INTRODUCTION: Enchondromas are benign, solitary bone tumors originating from hyaline cartilage, that are usually located in the upper and lower extremities. They are equally distributed in both genders and in all age groups. Approximately 40-65% of the cases are located in the small tubular bones of the hand, and the proximal phalanx, metacarpal bones, middle phalanx are frequently involved; involvement of the distal phalanx is quite rare. The aim of this study was to investigate the pre-operative white blood cell count, neutrophil count, red cell distribution width, mean corpuscular volume, platelet count, hemoglobin, hematocrit and NLR values, and make a comparison with a control group. The most commonly involved sites are also investigated in the patient group.
METHODS: This retrospective study investigated the preoperative WBC, neutrophil, lymphocyte, RDW, MCV and NLR values in 20 patients and 20 controls, and compared the frequency of the involved sites among patients with enchondroma.
RESULTS: No statistically significant difference was determined between the groups with regard to WBC, neutrophil count, MCV, RDW. While the NLR values were different between the groups, there was no statistically significant difference. Involvement of the proximal phalanx was statistically significantly higher (p<0.05).
DISCUSSION AND CONCLUSION: This is the first study investigating the pre-operative RDW, MCV, NLR, PLT, Hgb, Hct and WBC in patients with enchondroma. While no statistically significant difference was determined between the groups with regard to these parameters, we suggest that they should be studied in larger groups and in clinical tests, so that the malignancy potential may be predicted.