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Cardiac Function in Chronic Obstructive Pulmonary Disease: Role of MAPSE
Yeliz Guler1, Hüseyin Akgün1, Ufuk SALİ HALİL1, Şevval Kılıç1, Gamze Acar1, Damla Azaklı2, ahmet guler1, Sibel Yurt21University Of Health Sciences, Basaksehir Cam&sakura City Hospital, Department Of Cardiology, Istanbul-tr2University Of Health Sciences, Basaksehir Cam&sakura City Hospital, Department Of Pulmonology, Istanbul-tr
INTRODUCTION: This study aims to investigate the role of mitral annular plane systolic excursion (MAPSE) in evaluating left ventricular function in patients with chronic obstructive pulmonary disease (COPD).
METHODS: This study included 53 COPD patients and 51 healthy controls. All participants underwent echocardiographic evaluation, including tissue Doppler imaging. Lateral MAPSE was measured via M-mode in the apical four-chamber view.
RESULTS: The mean age of the study population was 63.5 ± 8.8 years, with 69.2% male. No significant differences were observed between the COPD (n=53) and control (n=51) groups regarding age, sex, heart rate, blood pressure, comorbidities, or laboratory findings, though smoking was more prevalent in the COPD group. Pulmonary function tests showed significantly lower FEV₁ and FEV₁/FVC in COPD patients (p<0.001). Conventional echocardiographic parameters including left ventricular dimensions and ejection fraction were similar between groups. However, the COPD group exhibited higher LAVi and e/E′ ratios, lower E′ velocities, and impaired right ventricular function indicated by reduced TAPSE and Sm-RV and elevated PAPs (all p<0.001). Importantly, MAPSE values were significantly decreased in COPD patients, reflecting impaired longitudinal left ventricular function [11.3 (9.6–13.8) vs. 13.7 (13.4–15.2), p<0.001].
DISCUSSION AND CONCLUSION: Reduced MAPSE in COPD patients may indicate early LV systolic dysfunction. MAPSE is a simple and reliable parameter that may aid in the early detection of cardiac involvement in COPD.
Manuscript Language: English