INTRODUCTION: Several studies have assessed the association between blood group of ABO and many cancer. Nevertheless, there was no data regarding the connection between blood group of ABO and tumor diameters in carotid body tumors (CBTs) patients. The purpose of our study was to analyses possible association between tumor diameters and gender, ABO blood group in CBTs patients compared healthy controls.
METHODS: The demographic and laboratory data of 65 CBTs patients (57 females and 8 males) who underwent surgical intervention and 65 healthy controls (52 females and 13 males) were retrospectively analyzed.
RESULTS: The mean age of CBTs patients was 51.81±9.82 years, and the mean age of the healthy subjects was 52.72±8.50 years. There were no statistically significant between two groups with regard to age and gender. The mean of tumor diameters was 3.72±1.50 cm (range=1-8 cm). There was no statistically significant difference between study groups according to AB0 blood group (p=0.87). The females/males ratio of patients was 57/8. The mean tumor diameters of females was 3.57±1.34 cm and the mean tumor diameters of males was 4.77±2.16 cm; the difference was statistically significant (p=0.03). There was a positive correlation between male gender and the tumor diameters (r=0.23, p=0.03).
DISCUSSION AND CONCLUSION: This is the first report investigating association between the tumor diameters and AB0 blood group in CBTs. Although CBTs were shown higher in females, tumor diameters were found significantly higher in males than females. However, we did not determine any association between AB0 blood group and tumor diameters.