Is there a relationship between Helicobacter Pylori Eradication and Blood Group?

INTRODUCTION: Although there is an association between Helicobacter Pylori (HP) infection and blood group, the effect of blood groups on HP eradication is not yet known. Our aim in the study was to investigate the relationship between blood group and other risk factors with HP eradication after HP eradication therapy.
METHODS: 104 patients who underwent gastrointestinal system endoscopy and received gastric tissue biopsies were enrolled in the study at our hospital between June 2017-December 2018. Demographic and histopathological data of all patients were documented. HP eradication was performed by giving Amoxicillin and Clarithromycin and Pantoprazole treatment to all patients. Patients were divided into two groups according to HP eradication. The relationship between HP eradication rate and blood groups and risk factors was analyzed.
RESULTS: A total of 104 HP positivity was included in the study. The mean age of the patients was 47.7±14.6 years old. Fifty-two (50%) patients were women, the body mass index (BMI) was 27.6±4.7 (range: 17.7-42.1). The distrubition of blood groups were 49(47.1%) A, 13(12.5%) B, 9(8.7%) O, 33(31.7%) AB. HP eradication occurred in 70 (67.3%) patients after HP treatment. HP eradication rate was significantly higher in women, but there was no significant relation between HP eradication and age, BMI or blood groups.
DISCUSSION AND CONCLUSION: In conclusion, while there was a significant relationship between gender and HP eradication, no significant relationship was observed between ABO blood groups and HP eradication.