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Obstetric outcomes of women with ELISA positivity for HBV, HCV or HIV
Seçil Yücel Güven1, Sebile Güler Çekiç2, Sadık Gündüz3, Alev AYDlN41Obstetrics and Gynecology Department, Biga State Hospital, Canakkale, Turkey2Obstetrics and Gynecology Department, Koc University Hospital, Istanbul, Turkey
3Obstetrics and Gynecology Department, Sadi Konuk Research and Training Hospital, Istanbul, Turkey
4Obstetrics and Gynecology Department, Kanuni Sultan Süleyman Research and Training Hospital, Istanbul, Turkey
INTRODUCTION: ELISA-positivity for Hepatitis B Virus (HBV), Hepatitis C Virus (HCV) and Human Immunodeficiency Virus (HIV) may be related with negative obstetric outcomes. The aim of the study is to compare the pregnancy complication rates of pregnant women based on ELISA-positivity.
METHODS: In this retrospective study, obstetric outcomes of ELISA-positive and ELISA-negative pregnant women who admitted to the delivery room unit of Kanuni Sultan Suleyman Training and Research Hospital between January 2014 and December 2014 were examined. Patients were grouped into two groups in terms of ELISA positivity and negativity for HBV, HCV and HIV. In the study, 380 ELISA-positive and 294 ELISA-negative pregnant women were examined.
RESULTS: The demographic characteristics of both groups of were similar. No statistically significant difference was observed between the two groups in the average age, delivery method, premature birth, preterm membrane rupture (PROM), gestational diabetes mellitus (GDM), preeclampsia, intrahepatic cholestasis of pregnancy (ICP), poly/oligohydramnios, placenta previa, and congenital anomaly rates. The presence of fetal growth restriction (FGR), gestational hypertension (GHT) and increased pregnancy loss in the ELISA-positive group were found to be significantly higher than in the ELISA-negative group.
DISCUSSION AND CONCLUSION: In our study, we observed that the FGR and GHT rates of the ELISA-positive group were significantly higher than the ELISA-negative pregnant women, and their average birth weight was significantly lower. Therefore, we recommend that pregnancy follow-up in patients with positive serology be evaluated from these aspects.
Manuscript Language: English