Determination of post-transplant diseases in kidney donors and investigation of risk factors

INTRODUCTION: Kidney donors are followed up periodically for health problems such as chronic renal failure (CRF), hypertension (HT), diabetes mellitus (DM) that may develop after transplantation. The aim of this study was to determine the disease and to investigate the risk factors in renal donors followed in the outpatient clinic of the Nephrology.


METHODS: In this study, 40 patients with renal donors aged between 18-75 years who were admitted to the nephrology clinic were included. From all donors; anamnesis was taken to determine if there was any disease after kidney transplantation and physical examinations were performed.
Donors have previously looked at; 24-hour urinary glomerular filtration rate (GFR) and proteinuria measurement, creatinine, alanine aminotransferase (ALT), fasting glucose, hemoglobulin A1c (HgbA1c) values were recorded. According to the physical examination and laboratory results of the donors, systemic disease after transplantation and risk factors were evaluated

RESULTS: Of the 40 donors included in the study, 29 (72%) were female and 11 (18%) were male. In the post-transplant background; 3 (7.5%) had DM, 6 (15%) had HT and 1 (2.5%) had both DM and HT. The mean GFR was 81.62 ± 21.31 ml / min. The viral markers of the donors were negative for anti-HCV, anti-HIV and HbsAg
DISCUSSION AND CONCLUSION: As a result of the study, the incidence of diseases such as DM, HT, CRF in the follow-up of kidney donors admitted to our clinic was found to be the same as in the community.The fact that the incidence of donor diseases after transplantation is the same as the incidence in the community leads to a better option in the treatment of end-stage renal disease