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Therapeutic Curettage On Follow Up Human Chorionic Gonadotropin Levels in Ectopic Pregnancy [Eastern J Med]
Eastern J Med. Ahead of Print: EJM-26818 | DOI: 10.5505/ejm.2019.26818  

Therapeutic Curettage On Follow Up Human Chorionic Gonadotropin Levels in Ectopic Pregnancy

Melih Bestel1, Onur Karaaslan2, Ayşegül Bestel1, Süleyman Salman3
1Obstetric And Gynecology Clinic, Tekirdag State Hospital, Tekirdag, Turkey
2Obstetric And Gynecology Clinic, Hakkari State Hospital, Hakkari, Turkey
3Obstetric And Gynecology Clinic, University Of Health Sciences Gaziosmanpaşa Taksim Research And Training Hospital, İstanbul, Turkey

INTRODUCTION: In this study, we aimed to investigate the effect of therapeutic curettage and adjuvant metotrexate treatment on follow up human chorionic gonadotropin levels in ectopic pregnancy.
METHODS: Twenty-five patients who received methotrexate treatment out of 57 patients with a diagnosis of ectopic pregnancy and who completed their treatment at the hospital between 2016-2017 were included in the study. With random grouping, curettage was performed in 14 patients and was not performed in 11 patients. The percentage of changes in serum human chorionic gonadotropin levels between days 1 and 4, days 4 and 7, and days 1 and 7 were compared.
RESULTS: Comparing two groups, there was no statistically significant difference between the percentages of changes in serum human chorionic gonadotropin levels.
DISCUSSION AND CONCLUSION: Early diagnosis and treatment of ectopic pregnancy, an important cause of maternal mortality in the first trimester, is crucial. Regarding the surgical burden and no significant changes in serum levels of human chorionic gonadotropin in patients treated with therapeutic curettage and concurrent methotrexate treatment, curettage should be performed in selected patients or in patients with difficulty in diagnosis.

Keywords: ectopic pregnancy, methotrexate, serum human chorionic gonadotropin, therapeutic curettage




Corresponding Author: Melih Bestel, Türkiye


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