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A Retrospective Analysis of Haemotologic Parameters in Patients with Bilateral Tinnitus [Eastern J Med]
Eastern J Med. 2018; 23(4): 264-268 | DOI: 10.5505/ejm.2018.02703  

A Retrospective Analysis of Haemotologic Parameters in Patients with Bilateral Tinnitus

Ufuk Düzenli1, Nazım Bozan1, Mehmet Aslan2, Hüseyin Özkan1, Mahfuz Turan1, Ahmet Faruk Kıroğlu1
1Department of Otorhinolaryngology, Faculty of Medicine, Yüzüncü Yıl University, Van, Turkey
2Department of Internal Medicine, Faculty of Medicine, Yüzüncü Yıl University, Van, Turkey

INTRODUCTION: Tinnitus is a perception disorder of sound. Beside otologic diseases; mood disorders, inflammatory diseases, thromboembolic pathologies may lead to tinnitus. Mean platelet volume (MPV), Platelet Distribution Width (PDW) and Neutrophil-to-Lymphocyte Ratio (NLR) were investigated as biomarkers in tinnitus patients. In this study, we aimed to find whether there is any association between these biomarkers and bilateral tinnitus patients.
METHODS: Fifty eight with tinnitus and 58 healthy subjects were included to study. Distribution of age and sex in each group were equal. Hearing thresholds of tinnitus patients were obtained with pure-tone audiometry. Haemotologic values was evaluated in each group and correlation between these values and audiometric data were investigated in tinnitus patients.
RESULTS: PDW values of tinnitus group were found statictically significant higher than control group values (p=0.041). NLR was found lower in tinnitus patients and it was statistically significant (p=.001). MPV values were found similar in each group. In tinnitus group there were no correlation between haemotologic values and audiometric data.
DISCUSSION AND CONCLUSION: In this study we found blood marker value alterations in bilateral tinnitus patients but there were no correlation with audiologic data. And so we need larger studies to reach more significant results.

Keywords: Tinnitus, Mean Platelet Volume, Platelet Distribution Width, Neutrophil to Lymphocyte ratio, Haemotologic Biomarker


Ufuk Düzenli, Nazım Bozan, Mehmet Aslan, Hüseyin Özkan, Mahfuz Turan, Ahmet Faruk Kıroğlu. A Retrospective Analysis of Haemotologic Parameters in Patients with Bilateral Tinnitus. Eastern J Med. 2018; 23(4): 264-268

Corresponding Author: Ufuk Düzenli, Türkiye


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